DoseID Methods

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DoseID converts patient inputs into normalized metrics, applies indication-specific logic, and returns reference-dose suggestions with transparent intermediate values.

1) Unit Normalization and Body-Size Metrics

Weight and height entries are normalized before calculations. The app computes total body weight (TBW), ideal body weight (IBW), adjusted body weight (AdjBW), lean body weight (LBW), and BMI.

IBW (male) = 50 + 2.3 × (inches over 60)

IBW (female) = 45 + 2.3 × (inches over 60)

AdjBW = IBW + 0.4 × (TBW − IBW)

BMI = weight(kg) / height(m)^2

2) Renal Function Estimation

DoseID estimates creatinine clearance with Cockcroft-Gault and displays the weight used by the equation.

CrCl = ((140 − age) × weight) / (72 × SCr)

Female correction: CrCl × 0.85

In the creatinine pathway, renal bins based on CrCl are used for interval and dose adjustments. In iHD or CRRT pathways, dialysis templates override CrCl branching.

3) Dose Rule Engine

Each medication contains structured rules: indication options, weight-basis selection, renal pathway branching, and clinical notes. Regimens are generated from these rules at runtime.

Indication-specific branches (for example, CNS vs non-CNS pathways)
Renal pathway modes: standard, intermittent HD, CRRT
Weight-basis handling: TBW, IBW, AdjBW, or LBW depending on agent
Dose rounding for selected weight-based regimens

4) Scope and Safety

DoseID is an educational reference tool and not an autonomous prescribing system. Local formulary restrictions, infusion standards, dialysis schedules, therapeutic drug monitoring, and specialist review remain required for final orders.