Clinical Learning PlatformIDHub

Tool Overview

ProbID turns pretest thinking into a visible workflow by combining setting, findings, and likelihood ratios into an educational post-test estimate.

Use it for

CAP, VAP, endocarditis, invasive mold, and other syndromes where diagnostic uncertainty matters more than rote recall.

Interactive Tool

ProbID

Choose syndrome, location/setting, and features to estimate post-test probability using likelihood ratios. (Educational aid—not a guideline.)

Select features

Clinical syndrome

Pick location/setting + findings/tests in the catalog. Close it when done.

Location: Primary Care(Pretest 3.0%)

Selected findings/tests

None selected yet. Open the catalog to add.

Stepwise update

Choose findings/tests to see stepwise probability updates.

Fagan nomogram

Updating probability using likelihood ratios (Combined LR = 1.00)3.0%3.0%051015202530Pretest probability (%)0102030Post-test probability (%)
Multiplying LRs assumes conditional independence. Correlated inputs may overestimate certainty.

Post-test probability

Estimated probability
Pretest 3.0%
3.0%
Combined LR: 1.00
Educational estimate only. Always use clinical context.
Decision layer (MVP)

Harms are auto-estimated from syndrome + selected high-impact findings. Treatment threshold uses: P(treat) = Harm of unnecessary treatment / (Harm of unnecessary treatment + Harm of missed diagnosis).

Harm of missed diagnosis
10
Harm of unnecessary treatment
3
What is driving harm?
Baseline missed-diagnosis harm (CAP)10
Total missed-diagnosis harm10
Treatment threshold: 23%
Observation threshold: 12%
0%Observe ≤ 12%Treat ≥ 23%100%
Observe / monitor(Post-test 3.0%)
No additional high-impact risk modifiers selected; using syndrome baseline harms.
What’s driving it?

No selected findings yet.

Educational content only. Not medical advice. See references & methodology.

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Created by Alvaro Ayala, MD

Infectious Diseases Fellow at Stanford University, building a clearer, more useful home for case-based learning and clinical reasoning in ID.

Content is for learning purposes only and does not replace clinical judgment, institutional guidelines, or consultation with Infectious Diseases specialists. IDHub is an educational project focused on clinical teaching in Infectious Diseases.

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